Antifouling Studies of Unsymmetrical Oligo(ethylene glycol) Spiroalkanedithiol Self-Assembled Monolayers
نویسندگان
چکیده
The antifouling properties of self-assembled monolayers (SAMs) on gold generated from custom-designed bidentate unsymmetrical spiroalkanedithiols containing both oligo(ethylene glycol) and hydrocarbon tailgroups (EG3C7-C7 EG3C7-C18) were evaluated compared to SAMs derived analogous monodentate octadecanethiol (C18SH) the tri(ethylene glycol)-terminated alkanethiol EG3C7SH. Complementary techniques, including in situ surface plasmon resonance spectroscopy (SPR), ex electrochemical quartz crystal microbalance (QCM) measurements, ellipsometric thickness employed assess protein resistance using proteins having a wide range sizes, structures, properties: protamine, lysozyme, bovine serum albumin (BSA), fibrinogen. studies found that adsorbates EG3C7-C7 EG3C7-C18, which contain 1:1 mixture OEG tailgroups, exhibited diminished capacity resist adsorption EG3C7SH SAMs, possess only tailgroups. data highlight critical role hydration matrix for generating OEG-based coatings.
منابع مشابه
Antifouling properties of oligo(lactose)-based self-assembled monolayers.
The antifouling (AF) properties of oligo(lactose)-based self-assembled monolayers (SAMs), using four different proteins, zoospores of the green alga Ulva linza and cells of the diatom Navicula incerta, were investigated. The SAM-forming alkylthiols, which contained 1, 2 or 3 lactose units, showed significant variation in AF properties, with no differences in wettability. Non-specific adsorption...
متن کاملAntifouling self-assembled monolayers on microelectrodes for patterning biomolecules.
We present a procedure for forming a poly(ethylene glycol) (PEG) trimethoxysilane self-assembled monolayer (SAM) on a silicon substrate with gold microelectrodes. The PEG-SAM is formed in a single assembly step and prevents biofouling on silicon and gold surfaces. The SAM is used to coat microelectrodes patterned with standard, positive-tone lithography. Using the microtubule as an example, we ...
متن کاملSelf-Assembled Monolayers Generated from Unsymmetrical Partially Fluorinated Spiroalkanedithiols.
Self-assembled monolayers (SAMs) were prepared on gold substrates from an unsymmetrical partially fluorinated spiroalkanedithiol adsorbate with the specific structure of [CH3(CH2)7][CF3(CF2)7(CH2)8]C[CH2SH]2 (SADT) and compared to SAMs formed from the semifluorinated monothiol F8H10SH [CF3(CF2)7(CH2)10SH] of analogous chain length and n-octadecanethiol. The adsorbate with two alkyl chains, one ...
متن کاملSingle-step DNA immobilization on antifouling self-assembled monolayers covalently bound to silicon (111).
Hydrosilylation of alkenes with epoxide-terminated tri(ethylene oxide) moieties on Si-H surfaces yields homogeneous monolayers for the efficient coupling of biomolecules. The wetting properties of the epoxide-functionalized surface allow for the spotting of solutions of biomolecules, making the surface amenable to microarraying. Immobilization of thiolated DNA was achieved in a single step to f...
متن کاملCrystallization on Self Assembled Monolayers
Over the past two decades, self assembled monolayers (SAMs) (Love et al., 2005; Smith et al., 2004; Ulman, 1996) have been extensively studied due to their many applications in various fields such as electrochemistry (Eckerman et al., 2010), biosensors (Nyquist et al., 2000), protein separation (Chun and Stroeve, 2002) and enantiomer separation (Mastai, 2009). SAMs are organic assemblies formed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Micro
سال: 2021
ISSN: ['2673-8023']
DOI: https://doi.org/10.3390/micro1010012